CBTTC

Children's Brain Tumor Tissue Consortium (CBTTC)

7 March 2019 and beyond MAINTENANCE WARNING: The CBTTC Harvest system is NOW experiencing intermittent downtime as we upgrade its Google Sign-In system. If you require help obtaining clinical samples or data during this time, please contact Elizabeth Appert at research@cbttc.org for assistance

Data and Inventory System

Query and explore research subject and biospecimen sample data by clicking the "Explore CBTTC" button below.

The CBTTC clinical data is undergoing revision and quality control review. If you require help obtaining clinical data during this time, please email the CBTTC for assistance.

Explore CBTTC Register

Registration is required prior to use of the site.
This document provides quick instructions on performing queries.

This query tool will provide you with access to the de-identified pediatric brain tumor specimens and annotated data that is currently available for research. The major specimen types include, flash frozen tissue, tissue in freezing media, blood, CSF and pathology slide images.

The longitudinal clinical data highlights includes; histology, location, treatments (surgery, chemotherapy and radiation), diagnosis type (Initial, Recurrent, Progressive...), demographics, cancer predisposition and follow up data every 6 months until 5 years after the initial diagnosis. This follow up schema restarts if there is a recurrence, progression or secondary malignancy.

By choosing from the specimen types and clinical data filters provided you can associate clinical information to a specimen or group of specimens of interest to answer a query, for example, "Are there specimens available from males under the age of 3 diagnosed with low grade glioma?"

Please email the CBTTC with questions or concerns.

For best performance, please use Chrome, Firefox or Safari.

About the CBTTC:

The Children's Brain Tumor Tissue Consortium (CBTTC) is a multi-institutional cooperative research program dedicated to the study of children's brain tumors. The ultimate goal of the CBTTC is to improve outcomes for children with brain tumors by supporting research on new prognostic biomarkers and therapies. The mission of the CBTTC is to collect high-quality brain tumor biospecimens with associated clinical data, facilitate genomic analysis of biospecimens, develop cell lines and transplantable tumor models from submitted biopsy specimens, and share results from these efforts with CBTTC member institutions and the world-wide scientific community. The long-term goal of the CBTTC is to actively stimulate tissue-based research and increase worldwide access to the molecular analysis of large numbers of brain tumor specimens by which new pediatric brain tumor therapeutic targets can be developed, and biologically-based prognostic factors essential to inform therapeutic decisions can be identified.

The CBTTC was initiated through a planning grant from the Children's Brain Tumor Foundation and support of the Licensing Industry Merchandiser's Association (LIMA). Current CBTTC participating institutions include

For more information about the CBTTC organizational structure and standard operating procedures (SOPs) please visit CBTTC.org.

About This Tool:

The CBTTC Data and Inventory System is a specific implementation of Harvest, a result of the collaboration between the Department of Biomedical and Health Informatics (DBHi) Enterprise Informatics team and the CBTTC.

Researchers can dynamically access the de-identified pediatric brain tumor specimens and annotated data currently available for use, all within an interface that allows for seamless reconciliation of integrated data types.