Designed with the modern biorepository in mind, the Biorepository Toolkit integrates key system components in a user-friendly interface to protect subject privacy, asynchronously collect data and deeply annotate growing institutional specimen, data and genomic repositories by integrating familiar tools.
A "soup-to-nuts" integrated and open solution for the modern translational science environment.
We believe in open source software and open-source our work. The Biorepository Toolkit and all integration work with non-proprietary systems is licensed under BSD 2-clause License.
The Biorepository Toolkit utilizes a custom client to REDCap allowing for flexible relation between REDCap projects, records and protected patient information while maintaining the flexibility of keeping form building cheap and easy.
Created by the Department of Biomedical and Health Informaticsat The Children's Hospital of Philadelphia Research Institute, the Biorepositoy Portal Toolkit fills a unique place in operating modern biorepositories and sharing precious scientific information to fuel discovery.
The Children's Brain Tumor Foundation, The Clinical and Translational Science Award (CTSA), The CHOP Center for Childhood Cancer Research (CCCR), The PennCHOP Microbiome Center and othershave funded this integrated toolkit.
Paper Published: Felmeister, A. S., Masino, A. J., Rivera, T. J., Resnick, A. C., and Jeffrey, W. (2016). The biorepository portal toolkit : An honest brokered , modular service oriented software tool set for biospecimen-driven translational research. BMC Genomics, 17(Suppl 4), 1–22. http://doi.org/10.1186/s12864-016-2797-9
Two studies reported in the Journal of Clinical Oncologyassessed the efficacy of a drug called vismodegib (Erivedge) in a subgroup of patients with recurrent medulloblastoma. Tom Curran, PhD, FRS, deputy scientific director of The Children’s Hospital of Philadelphia Research Institute, contributed to the article.
Adam C. Resnick, PhD recently participated in the Champions of Change Campaign in Precision Medicine at the White House. They were invited by the nonprofit Dragon Master Foudation in recognition of their pediatric brain tumor research.
A client to REDCap. Allowing study coordinators to associate multiple REDCap projects with a single honest-broker subject, and view or enter data de-identified into the forms on those projects.
A custom client to our enterprise LIMS system. Please contact us to discuss the details of this project.
Harvest:For all researcher-facing projects we utilize the open-source Harvestdata exploration platform to display de-identified specimen, clinical and genomic data on a project-by-project basis.
Screenshot from The Children's Brain Tumor Tissue Consortium. If you are part of the brain tumor research community and would like more information please check out the CBTTC Website . For access to this project, please goto CBTTC Data and Specimen Inventory Tooland apply for an account.