Enterprise Informatics

Applications

Biorepository Portal

The Biorepository Portal (BRP) is a federated web application used to support longitudinal biospecimen collection activities. Using HTTP protocols, it interfaces with downstream data systems, including REDCap and Thermo Scientific's Nautilus LIMS, to provide a single unified interface for data collection and update activities. It leverages the electronic honest broker to ensure that longitudinal data collection is performed in a manner compliant with NCI Best Practices for Biospecimen Resources.

Launch BRP Application

Harvest Deployments

CBTTC Data and Inventory System

The CBTTC is a multi-institutional cooperative research program dedicated to the study of childhood brain tumors. The ultimate goal of the CBTTC is to improve outcomes for children with brain tumors by supporting research on new prognostic biomarkers and therapies.

The CBTTC is a new paradigm for tissue research, not only collecting all types of childhood brain tumors but additionally performing analysis using cutting edge technologies while freely sharing the data with the scientific community at large to develop new treatments.

Launch CBTTC-Harvest Application

UPenn NTTB Data and Inventory System

The UPenn-CHOP Neurosurgery Tumor Tissue Bank (NTTB), a state-of-the-art brain tumor biorepository, is a collaborative effort between several departments at the University of Pennsylvania (Neurosurgery and Pathology) and the Children’s Hospital of Philadelphia (CHOP).

Under this collaborative, fresh tumor tissue is collected, processed, and stored for multiple downstream applications. In addition cell lines derived from primary brain tumors are also banked and available for the research community. We hope that this UPenn-CHOP Neurosurgery Tumor Tissue Bank collaborative will facilitate the development of personalized therapies through the characterization of each individual tumor at the genetic, epigenetic and proteomic level.

Launch UPennNTTB-Harvest Application

CCCR Data and Inventory System

The Center for Childhood Cancer Research (CCCR) is a Center of Emphasis at the CHOP Research Institute dedicated to translating the latest scientific findings obtained from cutting-edge basic research into innovative clinical trials designed to dramatically improve the cure rates for pediatric cancers while simultaneously eliminating long-term side effects. The CCCR Biorepository is a center-wide, general biobank, which supports CCCR’s mission through the collection and preservation of richly annotated biological specimens integrated with clinical phenotypic data.

Launch CCCR-Harvest Application (CHOP-internal)

Concussion Genomics Study

The Concussion Genomics Study consists of clinically abstracted data from CHOPs Department of Neurology. This study consists of clinical data abstraction with future laboratory integration possible. The Concussion Genomics study examines and compares child genomics after a concussion event. The EiG is paramount in integrating and maintaining their data using our BioRepository portal as well as an included Harvest instance.

To access the Concussion system,
please contact DBHi's Enterprise Informatics Group at:

e-mail CBMIsupport@email.chop.edu

Tobacco Grant Microbiome Study

The Microbiome study is a research study, run in CHOP’s Division of Gastroenterology, Hepatology and Nutrition, comparing the gut Microbiome of subjects with Inflammatory Bowel Disease and the Microbiome of those without. This is a longitudinal study consisting of integrated abstracted clinical and laboratory data. This study will try to better understand the microbiome in healthy pediatric patients and pediatric patients with IBD. It will further investigate the effects of antibiotic exposure, Clostridium difficile (C. difficile) infection, the metabolome, and human genetic variations on microbial populations in these children. The EiG are key players in this data maintenance, management and integration. The EiG is paramount in integrating and maintaining their data using our BioRepository portal as well as an included Harvest instance.

To access the Tobacco Grant Microbiome system,
please contact DBHi's Enterprise Informatics Group at:

e-mail CBMIsupport@email.chop.edu

IBD Biorepository

The IBD Biorepository is a collection of samples from multiple studies being run in CHOP’s Division of Gastroenterology, Hepatology and Nutrition. The IBD Biorepository consists of three studies using a common data set to annotate sample collection from these various studies. The IBD BioRepository utilizes the EiG’s BioRepository portal to login these samples and associate the specimen and laboratory data. A “Harvest” instance is in development for this study to allow for cohort discovery.

To access the IBD system,
please contact DBHi's Enterprise Informatics Group at:

e-mail CBMIsupport@email.chop.edu

Biorepository Portal Toolkit

Explore our Biorepository Portal Toolkit information page via brptoolkit.com for the toolkit or more information.